XVII. Treatment of advanced-stage Hodgkin lymphoma

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XVII. Treatment of advanced-stage Hodgkin lymphoma.

Advanced-stage Hodgkin lymphoma (HL) usually includes all patients diagnosed in Ann Arbor stages III and IV. Many groups also include patients with stage IIB and additional risk factors such as large mediastinal mass and/or extranodal disease. Historically, less than 5% of these patients survived when left untreated or received singleagent chemotherapy. With the development of multi-agent chemo...

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XVII. Radiotherapy in early stage Hodgkin lymphoma.

The treatment of patients with Hodgkin lymphoma (HL) is one of the major success stories in oncology and 60–90% of patients are cured of their malignancy depending on clinical stage and risk factors. Radiotherapy was used to cure patients with HL as early as the 1940s, but more widespread successes came in the 1960s for early stage diseases I A and II A with the use of extended field radiothera...

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Treatment of early-stage Hodgkin lymphoma.

Hodgkin lymphoma (HL) has become one of the best curable malignancies today. This is particularly true for patients with early-stage disease. Today, most patients in this risk group are treated with a combination of chemotherapy followed by small-field radiotherapy. More recent clinical trials such as the German Hodgkin Study Group (GHSG) HD10 study demonstrated, that even two cycles of ABVD fo...

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Treatment of Early Stage Hodgkin Lymphoma

Hodgkin lymphoma (HL) is an uncommon lymphoid malignancy which accounts for about 0.5% to 1% of all cancers. In 2010, an estimated 8,490 new cases and 1,320 deaths will occur in the United States (Jemal, Siegel, Xu, et al, 2010). HL incidence appears to be stable over the past few decades, in contrast to the incompletely understood continued increase in frequency of non-Hodgkin lymphomas. HL ha...

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Hodgkin Lymphoma and Anaplastic Variants of Non-Hodgkin Lymphoma

  Background and Objectives: Classic Hodgkin lymphoma (CHL), anaplastic large cell lymphoma (ALCL) and some cases of diffuse large B cell lymphoma (DLBCL) have overlapping morphologic features. Since they all represent distinct clinico-pathologic entities, we explored the differential diagnostic impact of immunophenotyping to discriminate between them. Materials and Methods:...

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ژورنال

عنوان ژورنال: Hematological Oncology

سال: 2015

ISSN: 0278-0232

DOI: 10.1002/hon.2225